Xenon in PDB 3pk6: Urate Oxidase Under 0.2 Mpa / 2 Bars Pressure of Xenon

All present enzymatic activity of Urate Oxidase Under 0.2 Mpa / 2 Bars Pressure of Xenon:
1.7.3.3;

The structure of Urate Oxidase Under 0.2 Mpa / 2 Bars Pressure of Xenon, PDB code: 3pk6 was solved by G.Marassio, N.Colloc'h, T.Prange, J.H.Abraini, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.70 / 1.80
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	80.066, 95.943, 105.308, 90.00, 90.00, 90.00
R / Rfree (%)	16.1 / 18.3

The structure of Urate Oxidase Under 0.2 Mpa / 2 Bars Pressure of Xenon also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Xenon atom in the Urate Oxidase Under 0.2 Mpa / 2 Bars Pressure of Xenon (pdb code 3pk6). This binding sites where shown within 5.0 Angstroms radius around Xenon atom.
In total only one binding site of Xenon was determined in the Urate Oxidase Under 0.2 Mpa / 2 Bars Pressure of Xenon, PDB code: 3pk6:

Xenon binding site 1 out of 1 in the Urate Oxidase Under 0.2 Mpa / 2 Bars Pressure of Xenon


Mono view


Stereo pair view

A full contact list of Xenon with other atoms in the Xe binding site number 1 of Urate Oxidase Under 0.2 Mpa / 2 Bars Pressure of Xenon within 5.0Å range: probe atom residue distance (Å) B Occ A:Xe801 b:30.6 occ:0.25 CD1 A:LEU252 3.8 21.3 1.0 CG2 A:THR230 3.8 19.8 1.0 CD1 A:PHE219 4.0 18.6 1.0 CB A:THR230 4.0 19.4 1.0 CD2 A:LEU178 4.1 22.2 1.0 CE1 A:PHE219 4.3 17.9 1.0 CG1 A:VAL227 4.3 16.7 1.0 CE A:MET234 4.3 22.5 1.0 O A:VAL227 4.4 16.0 1.0 CA A:VAL227 4.5 16.0 1.0 CG2 A:THR180 4.7 17.8 1.0 CB A:VAL227 4.8 15.0 1.0 N A:MET231 4.8 18.3 1.0 CG2 A:VAL227 4.8 16.8 1.0 CG A:LEU178 4.8 18.4 1.0 OG1 A:THR230 4.9 20.2 1.0 C A:VAL227 5.0 16.0 1.0

G.Marassio, T.Prange, H.N.David, J.Sopkova-De Oliveira Santos, L.Gabison, N.Delcroix, J.H.Abraini, N.Colloc'h. Pressure-Response Analysis of Anesthetic Gases Xenon and Nitrous Oxide on Urate Oxidase: A Crystallographic Study. Faseb J. V. 25 2266 2011.
ISSN: ISSN 0892-6638
PubMed: 21421845
DOI: 10.1096/FJ.11-183046