Xenon in PDB 1vau: Xenon Derivative of Hen Egg-White Lysozyme

All present enzymatic activity of Xenon Derivative of Hen Egg-White Lysozyme:
3.2.1.17;

The structure of Xenon Derivative of Hen Egg-White Lysozyme, PDB code: 1vau was solved by K.Takeda, H.Miyatake, S.Y.Park, M.Kawamoto, N.Kamiya, K.Miki, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 1.50
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	78.330, 78.330, 36.940, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 20.3

The structure of Xenon Derivative of Hen Egg-White Lysozyme also contains other interesting chemical elements:

Chlorine	(Cl)	2 atoms
Sodium	(Na)	1 atom

The binding sites of Xenon atom in the Xenon Derivative of Hen Egg-White Lysozyme (pdb code 1vau). This binding sites where shown within 5.0 Angstroms radius around Xenon atom.
In total 3 binding sites of Xenon where determined in the Xenon Derivative of Hen Egg-White Lysozyme, PDB code: 1vau:
Jump to Xenon binding site number: 1; 2; 3;

Xenon binding site 1 out of 3 in the Xenon Derivative of Hen Egg-White Lysozyme


Mono view


Stereo pair view

A full contact list of Xenon with other atoms in the Xe binding site number 1 of Xenon Derivative of Hen Egg-White Lysozyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Xe201 b:18.9 occ:0.22 CD1 A:ILE55 2.5 18.3 0.8 CG1 A:ILE55 3.4 13.6 0.8 CD1 A:ILE55 3.6 17.6 0.2 CG2 A:VAL92 3.7 11.9 1.0 CD1 A:LEU56 3.7 10.2 1.0 CE A:MET12 3.7 11.3 1.0 CG1 A:ILE55 3.7 13.7 0.2 CB A:SER91 3.9 10.3 1.0 CG A:LEU56 4.1 8.3 1.0 N A:VAL92 4.2 10.4 1.0 CD1 A:ILE88 4.2 13.9 1.0 CB A:ILE88 4.3 11.4 1.0 C A:SER91 4.4 10.4 1.0 CA A:VAL92 4.5 10.5 1.0 CB A:ILE55 4.6 11.2 0.2 O A:ILE88 4.6 11.3 1.0 CB A:ILE55 4.7 11.7 0.8 CG A:MET12 4.7 11.4 1.0 CD1 A:LEU17 4.7 12.9 1.0 CB A:VAL92 4.7 10.9 1.0 CG1 A:ILE88 4.7 12.8 1.0 O A:SER91 4.8 10.3 1.0 CG2 A:ILE88 4.8 12.4 1.0 CA A:SER91 4.8 10.3 1.0 OG A:SER91 4.9 10.0 1.0

Xenon binding site 2 out of 3 in the Xenon Derivative of Hen Egg-White Lysozyme


Mono view


Stereo pair view

A full contact list of Xenon with other atoms in the Xe binding site number 2 of Xenon Derivative of Hen Egg-White Lysozyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Xe202 b:11.4 occ:0.23 OG1 A:THR43 3.4 12.3 1.0 N A:ARG45 3.7 13.0 1.0 N A:ASN44 3.7 11.3 1.0 CB A:THR43 3.8 10.3 1.0 CA A:ASN44 3.9 11.9 1.0 C A:ASN44 3.9 12.4 1.0 C A:THR43 3.9 11.0 1.0 O A:THR43 4.2 11.1 1.0 CB A:ARG45 4.2 14.2 1.0 NH2 A:ARG45 4.2 18.0 1.0 CG2 A:THR51 4.3 10.5 1.0 O A:HOH372 4.3 29.3 1.0 CA A:ARG45 4.4 13.8 1.0 CZ A:ARG45 4.6 18.5 1.0 CA A:THR43 4.6 10.5 1.0 O A:ASN44 4.6 12.2 1.0 NE A:ARG45 4.8 18.2 1.0

Xenon binding site 3 out of 3 in the Xenon Derivative of Hen Egg-White Lysozyme


Mono view


Stereo pair view

A full contact list of Xenon with other atoms in the Xe binding site number 3 of Xenon Derivative of Hen Egg-White Lysozyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Xe203 b:31.8 occ:0.32 O A:LEU129 3.7 22.7 1.0 C A:LEU129 4.1 22.6 1.0 CA A:LEU129 4.1 22.4 1.0 CB A:ALA10 4.2 11.2 1.0 O A:ARG128 4.4 22.1 1.0 CA A:ALA10 4.6 11.3 1.0 O A:ALA10 4.8 11.5 1.0 CD2 A:LEU129 4.9 24.1 1.0 OXT A:LEU129 5.0 23.9 1.0

K.Takeda, H.Miyatake, S.Y.Park, M.Kawamoto, N.Kamiya, K.Miki. Multi-Wavelength Anomalous Diffraction Method For I and Xe Atoms Using Ultra-High-Energy X-Rays From Spring-8 J.Appl.Crystallogr. V. 37 925 2004.
ISSN: ISSN 0021-8898