Xenon in PDB 1c6b: T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon

All present enzymatic activity of T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon:
3.2.1.17;

The structure of T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon, PDB code: 1c6b was solved by M.L.Quillin, B.W.Matthews, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.00 / 2.20
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	61.180, 61.180, 97.487, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / n/a

The structure of T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Xenon atom in the T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon (pdb code 1c6b). This binding sites where shown within 5.0 Angstroms radius around Xenon atom.
In total 2 binding sites of Xenon where determined in the T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon, PDB code: 1c6b:
Jump to Xenon binding site number: 1; 2;

Xenon binding site 1 out of 2 in the T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon


Mono view


Stereo pair view

A full contact list of Xenon with other atoms in the Xe binding site number 1 of T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon within 5.0Å range: probe atom residue distance (Å) B Occ A:Xe500 b:24.9 occ:0.77 SD A:MET102 3.7 21.6 1.0 CE A:MET102 3.9 14.3 1.0 CB A:PHE114 3.9 8.5 1.0 CD2 A:LEU118 4.0 23.3 1.0 CB A:SER117 4.0 12.9 1.0 CD1 A:LEU121 4.1 15.8 1.0 CD2 A:PHE114 4.2 24.1 1.0 CG A:PHE114 4.2 12.2 1.0 CG A:LEU118 4.5 19.4 1.0 CG1 A:VAL111 4.6 11.7 1.0 OG A:SER117 4.6 21.3 1.0 CE2 A:PHE153 4.6 19.6 1.0 XE A:XE501 4.6 24.7 0.5 N A:LEU118 4.7 14.0 1.0 CD1 A:LEU99 4.8 18.8 1.0 CZ A:PHE153 4.8 15.4 1.0 C A:SER117 4.9 12.6 1.0 CA A:LEU118 5.0 11.4 1.0 O A:PHE114 5.0 17.6 1.0

Xenon binding site 2 out of 2 in the T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon


Mono view


Stereo pair view

A full contact list of Xenon with other atoms in the Xe binding site number 2 of T4 Lysozyme Mutant C54T/C97A/L133A in the Presence of 8 Atm Xenon within 5.0Å range: probe atom residue distance (Å) B Occ A:Xe501 b:24.7 occ:0.46 CD2 A:PHE153 3.5 16.0 1.0 O A:ALA129 3.6 18.1 1.0 CG A:PHE153 3.8 18.9 1.0 CB A:PHE153 3.8 19.3 1.0 C A:ALA129 3.8 15.2 1.0 CB A:ALA133 3.9 9.4 1.0 N A:ALA130 4.1 9.9 1.0 CD2 A:LEU121 4.1 10.6 1.0 CB A:ALA129 4.2 14.3 1.0 CA A:ALA130 4.2 11.4 1.0 CE2 A:PHE153 4.2 19.6 1.0 CG A:LEU121 4.5 16.2 1.0 CA A:ALA129 4.6 13.0 1.0 CD1 A:LEU121 4.6 15.8 1.0 XE A:XE500 4.6 24.9 0.8 CG1 A:ILE150 4.7 18.3 1.0 CD1 A:PHE153 4.7 27.4 1.0 OG A:SER117 4.8 21.3 1.0 CB A:SER117 4.9 12.9 1.0 CA A:ILE150 5.0 7.6 1.0 CB A:ALA130 5.0 7.1 1.0

M.L.Quillin, W.A.Breyer, I.J.Griswold, B.W.Matthews. Size Versus Polarizability in Protein-Ligand Interactions: Binding of Noble Gases Within Engineered Cavities in Phage T4 Lysozyme. J.Mol.Biol. V. 302 955 2000.
ISSN: ISSN 0022-2836
PubMed: 10993735
DOI: 10.1006/JMBI.2000.4063