Xenon in PDB 1c62: T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon

All present enzymatic activity of T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon:
3.2.1.17;

The structure of T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon, PDB code: 1c62 was solved by M.L.Quillin, B.W.Matthews, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.00 / 2.30
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	61.252, 61.252, 97.014, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / n/a

The structure of T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Xenon atom in the T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon (pdb code 1c62). This binding sites where shown within 5.0 Angstroms radius around Xenon atom.
In total 2 binding sites of Xenon where determined in the T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon, PDB code: 1c62:
Jump to Xenon binding site number: 1; 2;

Xenon binding site 1 out of 2 in the T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon


Mono view


Stereo pair view

A full contact list of Xenon with other atoms in the Xe binding site number 1 of T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon within 5.0Å range: probe atom residue distance (Å) B Occ A:Xe500 b:18.8 occ:0.43 CD2 A:LEU118 3.6 13.8 1.0 CD2 A:LEU133 3.8 17.9 1.0 CD1 A:LEU121 3.9 8.8 1.0 CB A:PHE114 4.0 22.0 1.0 CE A:MET102 4.1 16.3 1.0 CG A:LEU118 4.1 25.0 1.0 CD1 A:LEU99 4.1 13.3 1.0 SD A:MET102 4.1 23.1 1.0 CG1 A:VAL111 4.2 9.5 1.0 CB A:SER117 4.2 15.4 1.0 CD2 A:PHE114 4.4 34.5 1.0 XE A:XE501 4.5 21.5 0.3 CG A:PHE114 4.6 20.5 1.0 N A:LEU118 4.6 10.1 1.0 O A:VAL111 4.6 20.2 1.0 O A:PHE114 4.7 21.4 1.0 CA A:LEU118 4.8 13.5 1.0 C A:SER117 4.8 15.3 1.0

Xenon binding site 2 out of 2 in the T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon


Mono view


Stereo pair view

A full contact list of Xenon with other atoms in the Xe binding site number 2 of T4 Lysozyme Mutant C54T/C97A/F153A in the Presence of 8 Atm Xenon within 5.0Å range: probe atom residue distance (Å) B Occ A:Xe501 b:21.5 occ:0.28 SD A:MET102 3.7 23.1 1.0 CB A:ALA98 3.8 11.1 1.0 CB A:ALA153 3.8 13.0 1.0 N A:LEU99 3.9 8.6 1.0 CA A:LEU99 3.9 9.8 1.0 CD1 A:LEU121 4.0 8.8 1.0 C A:ALA98 4.0 17.8 1.0 O A:ALA98 4.1 13.9 1.0 CD1 A:LEU99 4.2 13.3 1.0 CB A:LEU99 4.4 16.1 1.0 XE A:XE500 4.5 18.8 0.4 CA A:ALA98 4.6 18.7 1.0 CD1 A:LEU133 4.6 8.3 1.0 CD2 A:LEU121 4.8 10.8 1.0 O A:ARG95 4.9 27.2 1.0 CA A:ALA153 4.9 12.1 1.0 CG A:LEU99 4.9 20.0 1.0 CD2 A:LEU133 5.0 17.9 1.0 CG A:MET102 5.0 20.5 1.0

M.L.Quillin, W.A.Breyer, I.J.Griswold, B.W.Matthews. Size Versus Polarizability in Protein-Ligand Interactions: Binding of Noble Gases Within Engineered Cavities in Phage T4 Lysozyme. J.Mol.Biol. V. 302 955 2000.
ISSN: ISSN 0022-2836
PubMed: 10993735
DOI: 10.1006/JMBI.2000.4063